【作者】 黄璟; 陈智; 郭毅;
【Author】 HUANG Jing1,CHEN Zhi1,GUO Yi2 1.Department of Endodontics,Medical School of Stamotology,Wuhan University,Wuhan 430079,China; 2.Department of Epidemiology,School of Pubilc Health,Wuhan University,Wuhan 430071,China
【机构】 武汉大学口腔医学院; 武汉大学公共卫生学院流行病学教研室;
【摘要】 目的系统评价各种局部用氟预防儿童龋齿的效果。方法计算机检索e Cochrane Central Register ofControlled Trials(CENTRAL)、MEDLINE、EMbase、CKNI、VIP、WanFang Data、CBM以及灰色数据库[如Open Grey(opensigle.inist.fr)和National Technical Information Service(NTIS)等],纳入各种局部用氟预防儿童龋齿的随机对照试验(RCT),检索时间从1996年6月至2011年6月,同时手检相关专业杂志和资料。由两位评价员独立评价纳入研究的质量、进行资料提取和交叉核对后,采用RevMan 5.0软件进行Meta分析。结果纳入18个RCT,共19 359名儿童。8个RCT的Meta分析结果显示,氟保护漆组患龋率50.62%低于对照组患龋率70.89%,两组差异有统计学意义[OR=0.43,95%CI(0.34,0.55),P<0.000 01];4个RCT的Meta分析结果显示,氟离子透入组患龋率32.04%低于对照组患龋率44.94%,两组差异有统... 更多还原
【Abstract】 Objective To evaluate the effect of different topical fluorides for preventing dental caries in children.Methods Literature was searched according to the methods of systematic review in the following databases: CENTRAL,Medline,EMbase,CNKI,VIP,WanFang Data,CBM and Gray literature databases such as Open Grey and National Technical Information Service(NTIS) online,and the relevant journals and professional materials were also searched manually.The quality of the selected studies was appraised using... 更多还原 【关键词】 儿童龋齿; 预防; 局部用氟; Meta分析; 系统评价; 随机对照试验; 【Key words】 Children caries; Prevention; Topical fluoride; Meta-analysis; Systematic review; Randomized controlled trial;
【分类号】R781.1
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