【摘要】 目的:比较甲泼尼龙琥珀酸钠与氢化可的松治疗腹型过敏性紫癜的疗效。方法:将90例过敏性紫癜患儿随机分为两组。治疗组给予静脉滴注甲泼尼龙琥珀酸钠2 mg/kg,q 12 h;对照组给予氢化可的松8 mg/kg,q 12 h,两组治疗3 d后观察并比较疗效。结果:治疗组总有效率为89.6%,对照组总有效率为66.7%,两组疗效比较差异有统计学意义(2χ=7.0636,P<0.01);治疗组不良反应发生率10.42%,对照组不良反应发生率28.57%,两组比较差异有统计学意义(2χ=4.8188,P<0.05)。结论:甲泼尼龙琥珀酸钠治疗腹型过敏性紫癜优于氢化可的松,若因经济原因选用氢化可的松,需密切观察不良反应发生情况。 更多还原

【Abstract】 Objective:To compare the effect of methylprednisolone and hydrocortisone in abdominal allergic purpura.Methods: Ninety children with allergic pupura were randomly divided into two groups.Besides the same conventional therapy,the treatment group(n=48) was given intravenous drip with methylprednisolone sodium succinate(2 mg/kg,q 12 h) and the control group(n=42) was given hydrocortisone(8 mg/kg,q 12 h).Then the effects of the treatments in the two groups were observed and compared after 3 days.Res... 更多还原